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Jonathan Foulds, Ph.D., professor of public health sciences at Penn State (one of the two study sites), commented, This study shows that when smokers interested in reduction are provided with an e-cigarette with cigarette-like nicotine delivery, they are more likely to achieve significant decreases in tobacco-related toxicants, such as lower exhaled carbon monoxide levels. Additionally, the study's findings support limited safety concerns for the use of the specific e-cigarette/liquid combinations over the short term, even in the context of concurrent cigarette smoking